Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 30.00 | |
10 mg | In stock | $ 38.00 | |
25 mg | In stock | $ 52.00 | |
50 mg | In stock | $ 68.00 | |
100 mg | In stock | $ 101.00 | |
200 mg | In stock | $ 131.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 72.00 |
Description | Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. |
In vitro | Vecuronium inhibits both forms of the muscle-type acetylcholine receptor (IC50: 1-2 nM). Vecuronium combined with methylprednisolone shows additive effects on both receptor forms.[1] Vecuronium interferes with nicotinic processes in the carotid body and inhibits the chemoreceptor neural response to hypoxia. Vecuronium significantly attenuates the increase in CSNA (DeltaCSNA) in response to hypoxia in the carotid body.[2] |
In vivo | Vecuronium has a higher biliary clearance than pancuronium in the rats.[3] |
Synonyms | ORG NC 45 |
Molecular Weight | 637.73 |
Formula | C34H57BrN2O4 |
CAS No. | 50700-72-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 4 mg/mL (6.27 mM)
Ethanol: 93 mg/mL (145.8 mM)
DMSO: 93 mg/mL (145.8 mM)
You can also refer to dose conversion for different animals. More
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Vecuronium bromide 50700-72-6 Neuroscience AChR ORG NC45 ORG NC 45 Vecuronium Inhibitor muscle relaxant neurological disease ORG NC-45 nAChR inhibit Nicotinic acetylcholine receptors Vecuronium Bromide cancer nAChR inhibitor inhibitor